31 mai 2023
16:38 E.S.T.

Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies

Beatriz Aranda-Orgilles ; Isabelle Chion-Sotinel ; Jordan Skinner ; Steven Grudman ; Ben Mumford ; Chantel Dixon ; Jorge Postigo Fernandez ; Piril Erler ; Phillipe Duchateau ; Agnes Gouble ; Roman Galetto ; Laurent Poirot
Cancer Immunology Research

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12 mai 2023
04:57 E.S.T.

Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy

Shipra Das, Julien Valton, Philippe Duchateau, Laurent Poirot
Frontiers in Immunology

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10 novembre 2022
06:11 E.S.T.

Efficient multitool/multiplex gene engineering with TALE-BE

Alex Boyne, Alexandre Juillerat, Sylvain Pulicani, Maria Feola, Diane Tkach, Robert Hong, Aymeric Duclert, Philippe Duchateau
Frontiers in Bioengineering and Biotechnology

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30 juin 2022
09:43 E.S.T.

https://www.nature.com/articles/s41467-022-30896-2

Julien Valton, Shipra Das, Siumin Jo
Nature Communications

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28 avril 2022
09:01 E.S.T.

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Roman Galetto, Agnès Gouble
Nature Communications

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Publications scientifiques

Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies

Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy

Efficient multitool/multiplex gene engineering with TALE-BE

https://www.nature.com/articles/s41467-022-30896-2

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells