Scientific publications

Multi-armored allogeneic MUC1 CAR T cells enhance efficacy and safety in triple-negative breast cancer

Piril Erler, Tomasz Kurcon, Hana Cho, Jordan Skinner, Chantel Dixon, Steven Grudman, Sandra Rozlan, Emilie Dessez, Ben Mumford, Sumin Jo, Alex Boyne, Beatriz Aranda-Orgilles, Alexandre Juillerat, Philippe Duchateau and Laurent Poirot
Science Advances
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TALEN-edited Allogeneic Inducible Dual CAR T-cells Enable Effective Targeting of Solid Tumors while Mitigating Off-Tumor Toxicity

Sonal Dharani, Hana Cho, Jorge Postigo Fernandez, Alexandre Juillerat, Julien Valton, Philippe Duchateau, Laurent Poirot and Shipra Das
Molecular Therapy
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Comprehensive analysis of the editing window of C-to-T TALE base editors

Maria Feola, Sylvain Pulicani, Diane Tkach, Alex Boyne, Robert Hong, Louisa Mayer, Aymeric Duclert, Philippe Duchateau & Alexandre Juillerat
Scientific Reports
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Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells

Arianna Moiani, Gil Letort, Sabrina Lizot, Chloé Foray, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noémie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Anne Chalumeau, Tristan Felix, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre JUillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau & Julien Valton
Nature Communications
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TALEN-mediated intron editing of HSPCs enables transgene expression restricted to the myeloid lineage

Julien Valton, Philippe Duchateau, Alexandre Juillerat, Alex Boyne, Eduardo Seclen, Jessica C. Jang, Aminah O.Lawal, Sylvain Pulicani and Diane Tkach
Molecular Therapy
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