05 Nov 2014
08:38 E.S.T.

A platform for rapid prototyping of synthetic gene networks in mammalian cells

Xavier Duportet, Liliana Wroblewska, Patrick Guye, Yinqing Li, Justin Eyquem, Julianne Rieders, Tharathorn Rimchala, Gregory Batt & Ron Weiss
Nucleic Acids Res. 2014 Dec 1;42(21):13440-51. doi: 10.1093/nar/gku1082

15 Jul 2014
08:42 E.S.T.

Efficient Strategies for TALEN-mediated Genome Editing in Mammalian Cell Lines

Julien Valton, Jean Pierre Cabaniols, Roman Galetto, Fabien Delacote, Marianne Duhamel, Sebastien Paris, Dominique Alain Blanchard, Céline Lebuhotel, Severine Thomas, Sandra Moriceau, Raffy Demirdjian, Gil Letort, Adeline Jacquet, Annabelle Gariboldi, Sandra Rolland, Fayza Daboussi, Alexandre Juillerat, Claudia Bertonati, Aymeric Duclert, Philippe Duchateau
Methods Volume 69, Issue 2, September 2014, Pages 151–170 DOI: 10.1016/j.ymeth.2014.06.013

05 Jul 2014
14:00 E.S.T.

Exploring the transcription activator-like effectors scaffold versatility to expand the toolbox of designer nucleases

Alexandre Juillerat, Marine Beurdeley, Julien Valton, Séverine Thomas, Gwendoline Dubois, Mikhail Zaslavskiy, Jérome Mikolajczak, Fabian Bietz, George H Silva, Aymeric Duclert, Fayza Daboussi and Philippe Duchateau
BMC Molecular Biology 2014 doi:10.1186/1471-2199-15-13

29 Jun 2014
09:15 E.S.T.

BuD, a helix–loop–helix DNA-binding domain for genome modification

Stefano Stella, Rafael Molina, Blanca López-Méndez, Alexandre Juillerat, Claudia Bertonati, Fayza Daboussi, Ramon Campos-Olivas, Phillippe Duchateau and Guillermo Montoyaa
Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2042-52. doi: 10.1107/S1399004714011183.

17 Jun 2014
08:37 E.S.T.

Efficient design of meganucleases using a machine learning approach

Mikhail Zaslavskiy, Claudia Bertonati, Philippe Duchateau, Aymeric Duclert & George H Silva
BMC Bioinformatics. 2014 Jun 17;15:191. doi: 10.1186/1471-2105-15-191

12 Jun 2014
09:15 E.S.T.

Lentiviral protein delivery of meganucleases in human cells mediates gene targeting and alleviates toxicity

C He, A Gouble, A Bourdel, V Manchev, L Poirot, F Paques, P Duchateau, A Edelman and O Danos
Gene Therapy (2014) 21, 759–766; doi:10.1038/gt.2014.51

11 Jun 2014
09:00 E.S.T.

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Román Galetto, Celine Lebuhotel, Laurent Poirot, Agnès Gouble, Maria L Toribio, Julianne Smith, Andrew Scharenberg
Mol Ther Methods Clin Dev. 2014 Jun 11;1:14021. doi: 10.1038/mtm.2014.21

29 May 2014
13:00 E.S.T.

Genome engineering empowers the diatom Phaeodactylum tricornutum for biotechnology

Fayza Daboussi, Sophie Leduc, Alan Maréchal, Gwendoline Dubois, Valérie Guyot, Christophe Perez-Michaut, Alberto Amato, Angela Falciatore, Alexandre Juillerat, Marine Beurdeley, Daniel F. Voytas, Laurent Cavarec, Philippe Duchateau
Nat Commun. 2014 May 29;5:3831. doi: 10.1038/ncomms4831.

23 May 2014
13:30 E.S.T.

Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family

William Haun, Andrew Coffman, Benjamin M. Clasen, Zachary L. Demorest, Anita Lowy, Erin Ray, Adam Retterath, Thomas Stoddard, Alexandre Juillerat, Frederic Cedrone, Luc Mathis, Daniel F. Voytas and Feng Zhang
Plant Biotechnology Journal Volume 12, Issue 7 September 2014 Pages 934–940 DOI: 10.1111/pbi.12201

13 Mar 2014
09:57 E.S.T.

Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells

Rivière J, Hauer J, Poirot L, Brochet J, Souque P, Mollier K, Gouble A, Charneau P, Fischer A, Pâques F, de Villartay JP, Cavazzana M.
Gene Ther. 2014 Mar 13. doi: 10.1038/gt.2014.20.

Scientific publications

A platform for rapid prototyping of synthetic gene networks in mammalian cells

Efficient Strategies for TALEN-mediated Genome Editing in Mammalian Cell Lines

Exploring the transcription activator-like effectors scaffold versatility to expand the toolbox of designer nucleases

BuD, a helix–loop–helix DNA-binding domain for genome modification

Efficient design of meganucleases using a machine learning approach

Lentiviral protein delivery of meganucleases in human cells mediates gene targeting and alleviates toxicity

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Genome engineering empowers the diatom Phaeodactylum tricornutum for biotechnology

Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family

Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells